[LIVE] Rams vs 49ers Score (09/11/2026): 7 Key Injuries, Week 1 Result
Rams vs 49ers live Melbourne Sept 11 2026: score by quarter, 7 injuries Bosa Kittle Nacua, Week 1 scores, Fantasy and Week 2 odds.
Key takeaways
- Historic Week 1: first NFL regular-season game at Melbourne Cricket Ground, Sept 11 2026.
- Rams favored -3.5 (60.5% win prob ESPN), total 48.5.
- 7 key injuries: Bosa (knee), Kittle (Achilles), Nacua (groin), Garrett (knee), Juszczyk (finger), Evans (groin), Collins OUT.
- Rams are 4-1 vs 49ers in last 5 (42-26 on 11/09/25).
Rams vs 49ers, Sept 11 2026 at the Melbourne Cricket Ground: Rams favored -3.5, but 7 injuries (Bosa, Kittle, Nacua, Garrett) decide the real game. Score, injury table and Week 1 results below, updated live.
Updated Sept 11 2026 at 6pm UTC: Bosa and Kittle still questionable after Wednesday full practice for Juszczyk. Collins (49ers) ruled OUT. Bookmark this page for Week 2 odds.
Rams vs 49ers live score and quarter-by-quarter recap
This is the NFL Melbourne Game, the first regular-season NFL game ever played in Australia. The league scheduled 49ers vs Rams as Week 1 showcase at the MCG.
| Quarter | Rams | 49ers |
|---|---|---|
| Q1 | 0 | 3 |
| Q2 | LIVE | LIVE |
| Q3 | - | - |
| Q4 | - | - |
| Total | - | - |
Key team stats to watch (2025 meeting 42-26 Rams): total yards 401-393, turnovers 0-2, 3rd down 5/9 vs 3/8, red zone 5/6 vs 4/5, possession 32:32 vs 27:28. If San Francisco loses the turnover battle again, Melbourne ends the same way.
Check our football news hub for kickoff times and ticket info.
7 injuries that change everything
| Player | Team | Injury | Status | Est. return |
|---|---|---|---|---|
| Nick Bosa, DE | SF | Knee (ACL) | Questionable | Sept 10 game-time |
| George Kittle, TE | SF | Achilles | Questionable | Sept 10 game-time |
| Kyle Juszczyk, FB | SF | Finger | Full practice Wed | Likely plays |
| Mike Evans, WR | SF | Groin | Questionable | Sept 10 |
| Alfred Collins, DT | SF | - | OUT | - |
| Puka Nacua, WR | LAR | Groin | Questionable | Sept 10 |
| Myles Garrett, DE | LAR | Knee | Questionable | Sept 10 |
49ers: Bosa, Kittle, Juszczyk
Bosa traveled to Australia per Ian Rapoport. If he is limited, the Rams run game controls the edges. Kittle with an Achilles issue limits red-zone options. Juszczyk was a full participant Wednesday, good sign for short-yardage.
Rams: Nacua, Garrett
Nacua did not suit up in preseason. Without him, Davante Adams draws double coverage. Garrett (knee) is the pass-rush answer to Bosa. If both sit, expect a high-scoring, offensive-line dominated game and the Over 48.5 becomes live.
Fantasy and betting impact
- Start: Adams if Nacua sits, Kittle only if active, Rams D/ST as -3.5 favorites.
- Bench: Evans (groin + new offense), Collins replacements in IDP.
- Bet: Rams -3.5 only with Nacua active. Otherwise wait live. Lean Under if both edge rushers play full snaps.
Browse our shop for fan gear tested by our editors before Week 2.
All NFL Week 1 scores from the weekend
- Seahawks win opener despite Sam Darnold injury, defense steps up.
- Patriots lose: Maye turnovers + Brown injury, plenty of issues.
- Bears WR Rome Odunze (calf) limited going into Week 1.
- Jets: Breece Hall expected to play after groin strain.
- Cowboys TE Brevyn Spann-Ford agrees 3-year $18M deal.
- 49ers-Rams Melbourne closes Week 1 Thursday showcase.
Full standings and next fixtures are in our football section.
Head-to-head history: Rams own the rivalry lately
49ers are 1-4 vs Rams in last 5:
- 11/09/25: Rams 42 - 49ers 26
- 10/02/25 OT: 49ers 26 - Rams 23
- 12/12/24: Rams 12 - 49ers 6
- 09/22/24: Rams 27 - 49ers 24
- 01/07/24: Rams 21 - 49ers 20
Average: SF 2.4 TDs, 343 yards. LAR pass rush wins late. That is why Garrett vs Bosa availability matters more than the spread.
What is next: Week 2 odds and schedule
Winner takes early NFC West lead. If Bosa + Kittle stay limited, Rams take the division driver seat. Loser faces urgency in Week 2 home game.
External sources for live verification: ESPN gamecast, FOX Sports boxscore, NFL.com injury report.
Travel guide: getting to the MCG and official sources
Flying to Melbourne for the NFL Melbourne Game? The MCG sits in Yarra Park, 10 minutes walk from Flinders Street Station. Book trams, not taxis, on game day and arrive 90 minutes early for security and the pre-game show. Our travel tips cover stadium entry, bag policy and rain preparation, while resources help with roaming if you fly via Europe. For neutral verification see ESPN gamecast and NFL official game center for injury reports and play-by-play.
Frequently asked questions
Check the FAQ box at the top for quick answers on score, TV, Bosa, Nacua and favorites. This article stays online all season and the injury table is refreshed every Friday before Week 2 kickoff.
Season hub
Season pillar: continue with the NFL 2026 season guide — standings, injuries and Fantasy, updated weekly.